Factor V Leiden can cause blood clots in the legs (deep vein thrombosis) and lungs (pulmonary embolism). These blood clots can be life-threatening.

Is Factor V Leiden a high risk pregnancy?

The factor V Leiden mutation is associated with a slightly increased risk of pregnancy loss (miscarriage). Women with this mutation are two to three times more likely to have multiple (recurrent) miscarriages or a pregnancy loss during the second or third trimester.

Is Factor 5 Leiden bad?

People with factor V Leiden thrombophilia have a higher risk for blood clots. However, the severity of factor V Leiden thrombophilia varies greatly from person to person. Only 5% of people with one factor V Leiden mutation develop a clot by age 65.

How do you inherit Factor V Leiden?

Who is likely to have factor V Leiden (FVL)? FVL can only be inherited from a parent who has the mutation, which is more common among individuals of Northern European ancestry. Children from a parent with heterozygous FVL mutation have a 25% chance of having inherited it from the parent who has the mutation.

Does factor V Leiden affect menstruation?

Women who carry the factor V Leiden mutation lose less blood in menstruation, have higher haemoglobin levels, and possibly a lower incidence of life threatening post-partum haemorrhage, which could be an evolutionary advantage (Lindqvist et al., 2001).

Can you donate blood with factor V Leiden?

People with factor V Leiden may donate blood, platelets or plasma safely, as long as they are not on an anticoagulant such as warfarin. Only a very few medicines prevent people from donating blood.

Can Factor 5 Leiden donate blood?

Does aspirin help Factor V Leiden?

Though factor V Leiden alone does not seem to raise the risk of arterial clots, something as simple as daily therapy with low-dose aspirin may help prevent a heart attack or stroke in people with factor V Leiden if they have additional risk factors.

Should you wear a medical bracelet for factor V Leiden?

Blood thinners can cause serious bleeding problems. Let doctors you see know that you have factor V Leiden. Wear medical alert jewelry that lists your clotting problem.