Normal values for this test are less than 30 milligrams per deciliter (mg/dL). In many instances, people will have no detectable levels of Lp(a) in their bloodstream. If your results are greater than the 30 mg/dL threshold, this may indicate increased risk of atherosclerosis, heart attack, or stroke.

What is considered a high level of lipoprotein A?

In the US guidelines, elevated Lp(a)—defined as ≥ 50 mg/dL or ≥ 125 nmol/L—is considered a “risk-enhancing” factor that can be used to determine how aggressively to treat LDL cholesterol levels.

How high is too high for lipoprotein A?

Everybody should have their Lp(a) concentration measured once in their lifetime. CVD risk is elevated when Lp(a) concentrations are high i.e. > 50 mg/dL (≥100 mmol/L). Extremely high Lp(a) levels >180 mg/dL (≥430 mmol/L) are associated with CVD risk similar to that conferred by familial hypercholesterolemia.

Can lipoprotein A be lowered?

To achieve Lp(a) reduction, one evidence-based approach is to initiate therapy with low-dose aspirin and extended-release niacin, titrated from 0.5 g up to 2 g over several weeks.

Is lipoprotein A genetic?

Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein that is under strong genetic control by the LPA gene locus. Genetic variants including a highly polymorphic copy number variation of the so called kringle IV repeats at this locus have a pronounced influence on Lp(a) concentrations.

What causes high lipoprotein A?

Besides genetics, Lipoprotein (a) levels may result from increased intake of some types of fats, and some medical conditions. Treatment of elevated Lipoprotein (a) is based on a person’s risk of heart attack or stroke.

How is lipoprotein A inherited?

What does lipoprotein a test for?

A lipoprotein (a) test is used to check for risk of stroke, heart attack, or other heart diseases. It is not a routine test. It is usually only given to people who have certain risk factors, such as a family history of heart disease.

What is a lipoprotein (a)?

There are two main types of cholesterol: Low-density lipoprotein (LDL), or “bad” cholesterol. Lipoprotein (a) is a type of LDL (bad) cholesterol. A high level of lipoprotein (a) may mean you are at risk for heart disease. What is it used for? A lipoprotein (a) test is used to check for risk of stroke, heart attack, or other heart diseases.

What is the normal range for lipoprotein(a)?

The normal range for Lp (a) is <75 nmol/L or <30 mg/dL [ 15 ]. About 70% of people fall within this range [ 14 ]. Studies suggest that Lp (a) levels are higher in people of African descent than in people of European or Asian descent [ 16, 17 ]. Causes of High Lipoprotein (a) Levels

How can I lower my lipoprotein(a)?

There are no specific treatments to lower lipoprotein (a). Your level of lipoprotein (a) is determined by your genes and is not affected by your lifestyle or by most medicines.

What does it mean when your lipoprotein is high?

Causes of High Lipoprotein (a) Levels Lipoprotein levels above 75 nmol/L or 30 mg/dL indicate an increased risk of hardening of the arteries (atherosclerosis), heart disease, and stroke. Your doctor will interpret this test, taking into account your medical history, symptoms, and other tests.