Listen to pronunciation. (SIH-der-oh-PEE-nik dis-FAY-jee-uh) A disorder marked by anemia caused by iron deficiency, and a web-like growth of membranes in the throat that makes swallowing difficult. Having sideropenic dysphagia may increase the risk of developing esophageal cancer.

What clinical signs are typical for Sideropenic syndrome?

The most common among the latter are sores in the corners of the mouth, small atrophic lips, smooth, red tongue with pa- pillar atrophy, dysphagia and fingernail changes (koilonychia, brittle nails).

What is Plummer Vinson syndrome associated with?

Plummer-Vinson syndrome is a condition that can occur in people with long-term (chronic) iron deficiency anemia. People with this condition have problems swallowing due to small, thin growths of tissue that partially block the upper food pipe (esophagus).

Why does iron deficiency cause dysphagia?

Although the pathogenesis of PVS remains largely unknown, the most probable mechanism of PVS is iron deficiency [3], leading to rapid loss of iron-dependent enzymes due to its high cell turnover. Loss of these enzymes causes mucosal degenerations, atrophic changes and web formation, which are associated with dysphagia.

What is webbing in the esophagus?

An esophageal web is a thin (2-3 mm), eccentric, smooth extension of normal esophageal tissue consisting of mucosa and submucosa that can occur anywhere along the length of the esophagus but is typically located in the anterior postcricoid area of the proximal esophagus.

How common is Plummer-Vinson syndrome?

In the first half of the 20th century Plummer-Vinson syndrome seemed to be common in Caucasians of Northern countries, particularly among middle-aged women [8]. Nowadays, it is extremely rare.

What is Peterson Syndrome?

Listen to pronunciation. (PA-ter-sun-KEH-lee SIN-drome) A disorder marked by anemia caused by iron deficiency, and a web-like growth of membranes in the throat that makes swallowing difficult. Having Paterson-Kelly syndrome may increase the risk of developing esophageal cancer.

Can vitamin deficiency cause difficulty swallowing?

Dysphagia is an uncommon manifestation of vitamin B12 deficiency that is potentially reversible if diagnosed and treated within the first six months.

What is the treatment for dysphasia?

– Modifying the texture of foods and liquids. Diet modifications such as thickening liquids to a nectar-like consistency or pureeing foods in a blender can help a person with dysphagia maintain – Modifying the feeding environment. – General self-care.