Rapamune (sirolimus) is an immunosuppressive agent used to prevent your body from rejecting a transplanted kidney. Rapamune is sometimes used in a combination treatment with cyclosporine and a steroid medicine such as prednisone.

What is sirolimus used for?

Sirolimus is used together with other medicines to prevent the body from rejecting a transplanted kidney. It belongs to a group of medicines known as immunosuppressive agents. When a patient receives an organ transplant, the body’s white blood cells will try to get rid of (reject) the transplanted organ.

Is Rapamune the same as sirolimus?

Sirolimus, also known as rapamycin or by the brand name Rapamune, is a medicine that lowers the body’s natural immunity. The immune system response is thought to be involved in Nephrotic Syndrome. It is also used to prevent rejection of transplanted organs, such as the kidney, heart, and liver.

Is Rapamune the same as rapamycin?

Yes, sirolimus (Rapamune) and rapamycin are different names for the same medication. Scientists originally discovered the medication from a soil sample in Easter Island and named it rapamycin. The U.S. pharmaceutical world named the generic medication, sirolimus.

How do you take Rapamune?

Rapamune is to be administered orally once daily, consistently with or without food [see DOSAGE AND ADMINISTRATION, CLINICAL PHARMACOLOGY]. Tablets should not be crushed, chewed or split. Patients unable to take the tablets should be prescribed the solution and instructed in its use.

What is the cost of Rapamune?

The cost for Rapamune oral tablet 0.5 mg is around $1,669 for a supply of 100 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans….Oral Solution.

Is Rapamune an immunosuppressant?

Rapamune is a prescription medicine used to treat the symptoms of Prophylaxis of Renal Transplant Rejection and Lymphangioleiomyomatosis. Rapamune may be used alone or with other medications. Rapamune belongs to a class of drugs called Immunosuppressants.

When should I take sirolimus?

It is usually taken once a day, either always with food or always without food. To help you remember to take sirolimus, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Who makes Rapamune?

Pfizer Inc.
Pfizer Inc. (NYSE: PFE) announced today that the U.S. Food and Drug Administration (FDA) has approved RAPAMUNE® (sirolimus) for the treatment of lymphangioleiomyomatosis (LAM), a rare, progressive disease that affects the lungs, kidneys and the lymphatic system.

What is the generic brand for Rapamune?

GENERIC NAME: SIROLIMUS – ORAL (sir-oh-LEE-muss)

What kind of drug is sirolimus?

Sirolimus is in a class of medications called immunosuppressants. It works by suppressing the body’s immune system.

What is Rapamune available in pill form?

Rapamune is available for administration as an oral solution containing 1 mg/mL sirolimus. Rapamune is also available as a tan, triangular-shaped tablet containing 0.5 mg sirolimus, as a white, triangular-shaped tablet containing 1 mg sirolimus, and as a yellow-to-beige triangular-shaped tablet containing 2 mg sirolimus.

What is the maximum dose of Rapamune I can take?

The maximum Rapamune dose administered on any day should not exceed 40 mg. If an estimated daily dose exceeds 40 mg due to the addition of a loading dose, the loading dose should be administered over 2 days.

What is the difference between 2mg and 2Mg Rapamune oral solution?

Two milligrams (2 mg) of Rapamune Oral Solution have been demonstrated to be clinically equivalent to 2 mg Rapamune Tablets; hence, at this dose these two formulations are interchangeable.

What are the side effects of Rapamune for Lam?

The most common side effects of RAPAMUNE in people with LAM include: 1 mouth sores 2 diarrhea 3 stomach pain 4 sore throat 5 acne 6 nausea 7 chest pain 8 upper respiratory tract infection 9 headache 10 dizziness